Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Cellular Senescence
Normal mammalian cells in culture have a limited life span and will eventually maintain a growth arrested state, referred to as replicative senescence. Usually induced by telomere shortening this form of arrest is irreversible in the sense that cells cannot be triggered to reenter proliferation by physiological mitotic stimuli like growth factors. Senescence may also occur prematurely in respon...
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ژورنال
عنوان ژورنال: The Journal of Biochemistry
سال: 2014
ISSN: 0021-924X,1756-2651
DOI: 10.1093/jb/mvu040